Immunochemiluminometric assays based on acridinium labels with a microtiter plate luminometer
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چکیده
منابع مشابه
Immunochemiluminometric assays based on acridinium labels with a microtiter plate luminometer.
Inununoassays based on chemilunlinescent acridinium salts are highlysensitive, robust, and simple (1) but have not been demonstrated in a microplate format because of the lack of suitable luminometers with “on-board” reagent injection systems necessary for quantifying rapidchemiluminescent reactions. We report our initial studies on a two-site immunochemiluminometric assay (IcMA) for thyrotropi...
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Chemiluminescent acridinium dimethylphenyl ester labels are used in automated immunoassays for clinical diagnostics. Light emission from these labels is triggered by alkaline peroxide in the presence of the cationic surfactant cetyltrimethylammonium chloride (CTAC). The surfactant plays a critical role in the chemiluminescence process of these labels by both accelerating their emission kinetics...
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Chemiluminescent acridinium dimethylphenyl esters containing N-sulfopropyl groups in the acridinium ring are highly sensitive, hydrophilic labels that are used in automated immunoassays for clinical diagnostics. Light emission from these labels is triggered with alkaline peroxide in the presence of a cationic surfactant. At physiological pH, N-sulfopropyl acridinium esters exist as water adduct...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1991
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/37.3.472